Evaluation of studies of treatment or prevention interventions. Part 2: applying the results of studies to your patients.

Review of the clinical scenario You are a diabetes specialist nurse who, along with podiatrist colleagues, runs a foot care clinic for people with diabetes. A patient presents at the clinic with a full thickness plantar foot ulcer without any sign of arterial disease. The patient is enthusiastic to try an artificial skin replacement as she has read about them on the internet. You are unfamiliar with this type of wound covering, and your search for the best available evidence identified no systematic review and one randomised controlled trial (RCT). You are now getting to grips with this RCT before the patient’s next visit.